Aspergillus Galactomannan ELISA Nchọpụta ngwa
Okwu Mmalite ngwaahịa
FungiXpert® Aspergillus Galactomannan ELISA Detection Kit bụ ihe nyocha immunosorbent jikọtara ya na Enzyme maka nchọpụta qualitative nke Aspergillus galactomannan antigen na okenye na ụmụaka serum samples na bronchoalveolar lavage (BAL) mmiri sample.
Mmetụta nke Aspergillosis Invasive (IA) na ndị ọrịa na-egbochi ọgwụ mgbochi na-abawanye ngwa ngwa n'ihi iji ọgwụ nje eme ihe.IA nwere ọnụ ọgụgụ ọnwụ dị elu n'ihi enweghị ngosipụta ụlọ ọgwụ na-ahụkarị yana ụzọ nyocha mmalite dị irè.Aspergillus fumigatus bụ otu n'ime ọrịa nje na-ebutekarị ọrịa aspergillus na ndị ọrịa nwere ọrịa immunosuppressive, Aspergillus flavus, Aspergillus niger na Aspergillus terreus sochiri ya.
Njirimara
| Aha | Aspergillus Galactomannan ELISA Nchọpụta ngwa |
| Usoro | ELISA |
| Ụdị ihe atụ | Serum, mmiri mmiri BAL |
| Nkọwapụta | 96 ule/kit |
| Oge nchọpụta | 2 h |
| Ihe nchọpụta | Aspergillus spp. |
| Nkwụsi ike | Ngwa ahụ kwụsiri ike maka afọ 2-8 Celsius |
| Oke nchọpụta dị ala | 0.5ng/mL |
ndabere
Aspergillosis na-emerụ ahụ (IA)
Kedu ndị nwere ike ime
Ndị ọrịa nwere neutropenia ogologo oge, na-esote transplant ma ọ bụ na-ejikọta ya na usoro immunosuppressive ike.
Ọnọdụ dị elu
5% ruo 20%, dabere na ọnụ ọgụgụ ndị ọrịa.
Ọnụ ọgụgụ ọnwụ dị elu
50% ruo 80% n'ihi akụkụ ụfọdụ nke ọrịa na-aga n'ihu ngwa ngwa (ya bụ, izu 1-2 site na mmalite ruo ọnwụ).
Ọ siri ike ịchọpụta
O siri ike ịnweta ihe akaebe histopathological.Mmetụta nke ọdịbendị dị ala.≈30% nke ikpe na-anọgide na-achọpụtaghị na agwọghị ya mgbe ọnwụ.
Galactomannan (GM) ule
- Antigen a kapịrị ọnụ nke aspergillus dị na mgbidi cell nke ewepụtara n'oge oge uto nke aspergillosis na-emerụ ahụ.
- Ụbọchị 7 ruo 14 tupu ihe mgbaàmà ndị ọzọ apụta ìhè.
Ụkpụrụ
Uru
- Ọganihu ọzọ
Ụzọ nchọpụta ihu mba ụwa, nnukwu uche na nkọwapụta - Kazie ezi
Kwalite usoro ọrụ.Belata ihe ize ndụ nke mmetọ n'oge nnwale ahụ - Ọsọ ọsọ
Nchọpụta otu nzọụkwụ, na-ebelata ọnụ ọgụgụ nke incubation na oge ịsa ahụ
- Ọnụ ego karịa
Kewaa microplate, na-echekwa ọnụ ahịa - Nkwanye
Ntuziaka IDSA kwadoro maka Aspergillosis 2016 na ESCMID-ECMM-ERS ntuziaka maka Aspergillosis 2018
Mmetụta ụlọ ọgwụ
Nchọpụta mbụ
- GM bụ ụbọchị 5-8 tupu mgbe ahụ karịa mgbaàmà ụlọ ọgwụ nke aspergillosis invasive (IA);
- GM bụ ụbọchị 7.2 tupu CT nyocha dị elu;
- GM bụ ụbọchị 12.5 tupu mmalite nke ọgwụgwọ antifungal nke pụtara ìhè.
Nleba anya dị omimi
- GM dabara na ọnụọgụ ero ero, nke nwere ike igosipụta ogo ọrịa.
- Ọdịnaya nke GM antigen belatara site n'itinye ọgwụ antifungal.
Ntọala ahụike dị mkpa
- Belata iji ọgwụgwọ antifungal eme ihe.
- Mmekọrịta siri ike n'etiti nsonaazụ na GM index maka ọrịa cancer hematological.
Nchọpụta jikọtara ọnụ nke ule G na GM
- Nkọwa dị elu na uru amụma dị mma
- Mmetụta dị elu
Ozi ịtụ
| Nlereanya | Nkọwa | Koodu ngwaahịa |
| GMT-01 | 96 ule/kit | FGM096-001 |
