Ihe nchọpụta IMP nke Carbapenem na-eguzogide K-Set (Lateral Flow Assay) bụ usoro nyocha nke immunochromatographic ezubere maka nchọpụta qualitative nke ụdị carbapenemase nke IMP na mpaghara nje.Nnwale ahụ bụ nyocha ụlọ nyocha nke nwere ike inye aka n'ịchọpụta ụdị ụdị carbapenem na-eguzogide IMP.
Aha | Nchọpụta IMP nke Carbapenem na-eguzogide K-Set (Nchọpụta Ngosipụta N'azụ) |
Usoro | Nleba anya Flow Assay |
Ụdị ihe atụ | Ogbe nje bacteria |
Nkọwapụta | 25 ule / ngwa |
Oge nchọpụta | 10-15 min |
Ihe nchọpụta | Enterobacteriaceae na-eguzogide Carbapenem (CRE) |
Ụdị nchọpụta | IMP |
Nkwụsi ike | K-Set kwụsiri ike maka afọ 2 na 2°C-30°C |
Na mkpokọta, Enterobacterales bụ ndị na-ebutekarị ọrịa nje na-ebute ọrịa metụtara ahụike.Ụfọdụ Enterobacterales nwere ike ịmepụta enzyme a na-akpọ carbapenemase nke na-eme ka ọgwụ nje dị ka carbapenems, penicillins, na cephalosporins ghara ịdị irè.N'ihi nke a, a na-akpọ CRE "bacteria nro" n'ihi na ọ dị ole na ole ọgwụ nje ndị ọzọ, ma ọ bụrụ na ọ bụla, hapụrụ ịgwọ ọrịa nke nje ndị a kpatara.
Nje bacteria sitere na ezinụlọ Enterobacterales, gụnyere ụdị Klebsiella na Escherichia coli, nwere ike ịmepụta carbapenemase.A na-emepụtakarị carbapenemases site na mkpụrụ ndụ ihe nketa dị na ihe ndị nwere ike ibufe nwere ike gbasaa ngwa ngwa site na nje na nje na mmadụ gaa na mmadụ.Ọzọkwa n'ihi iji ọgwụ nje eme ihe n'ụzọ na-ezighị ezi na ụzọ ndị a kpaara ókè e mere iji gbochie mgbasa, nsogbu CRE na-arịwanye elu nke ukwuu na-aghọ ihe iyi egwu ndụ n'ụwa nile.
Ọtụtụ mgbe, enwere ike ịchịkwa mgbasa nke CRE site na:
……
Nchọpụta CRE bara uru dị ukwuu na njikwa mgbasa.Site na ịnwale n'oge, ndị na-ahụ maka ahụike nwere ike inye ndị ọrịa nwere ike ịnweta CRE ọgwụgwọ ezi uche dị na ya, nwetakwa njikwa ụlọ ọgwụ.
Carbapenemase na-ezo aka n'ụdị β-lactamase nke nwere ike ọ dịkarịa ala hydrolyze imipenem ma ọ bụ meropenem, gụnyere A, B, D ụdị atọ nke enzymes nke Ambler molecular Ọdịdị.N'ime ha, Klas B bụ metallo-β-lactamases (MBL), gụnyere carbapenemases dị ka IMP, VIM na NDM,.Ụdị carbapenemase nke IMP, nke a makwaara dị ka imipenemase metallo-beta-lactamase na-emepụta CRE, bụ ụdị MBL ndị a na-enwetakarị ma si na subclass 3A.Ọ nwere ike imebi ihe fọrọ nke nta ka ọ bụrụ ọgwụ nje β-lactam niile.
Nlereanya | Nkọwa | Koodu ngwaahịa |
CPI-01 | 25 ule / ngwa | CPI-01 |